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Medical University of South Carolina UNIV - Research Specialist II - Orthopaedics in Charleston, South Carolina

FLSA: Hourly

Job Summary: Under direction of the principal investigator, in collaboration physicians, and in cooperation with multiple laboratory members, the successful applicant will work within our group to perform and train other lab members in experiments on human and mouse tumor samples to metabolic pathways that contribute to productive immunity in cancers. Specifically, the research specialist will perform a high volume of highly specialized experiments including flow cytometry-based metabolism assays on mouse and human samples, monitoring of tumor experiments in mouse models, and performing molecular assays (ie. Western blotting). The candidate will be expected to work independently under the supervision of PI and lab manager, to contribute intellectually at laboratory meetings through paper presentations and sharing of data, and to serve as a technical consultant to incoming graduate students and other lab staff. Organization and efficiency are required. The candidate will have access and interface time with surgical and medical oncologists within our research group and the position may appeal to those seeking to attend graduate and/or medical schools.

Payscale Salary Range: UNIV-Band 5: $33,494.00 - $47,734.00 - $61,975.00 (min - mid - max)

Job Duties:

  • 30% - Perform high volumes of in vitro molecular and metabolic assays: Flow cytometry, RT-PCR, Western blotting, advanced tissue culture techniques. - (Essential)

  • 20% - Genotyping/Animal Management. The successful candidate will oversee animal colony management including weekly tracking of animal census, performing PCR genotyping of genetically modified animal strains, and determination of TCR transgenic specificity. - (Essential)

  • 20% - In vivo experiments that include processing mouse tumor samples for flow cytometry and molecular analysis, and monitoring in vivo tumor mouse models and treatments. - (Essential)

  • 10% - Human tumor samples processing and metabolic assay performance - (Essential)

  • 10% - Training of new lab members in molecular and metabolic assays - (Essential)

  • 5% - Preparation and review of manuscripts for scientific publication. - (Essential)

  • 5% - Other duties as assigned. - (Essential)

Minimum Experience and Training Requirements: A bachelor's degree in chemistry, biology, or other natural, life or health care science and one year work experience directly related to the assigned research area.

Additional Knowledge, Skills, and Abilities Preferred: Must be proficient in Microsoft Office software. Previous laboratory experience required. Experience with molecular and/or immunological investigations desired.

Physical Requirements: Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb, using step stool. (Infrequent) Ability to work in temperature extremes (32? F to 100? F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs., unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted. (Frequent) Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted. (Infrequent) Ability to lift file boxes, from floor level to counter tops, unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted. (Infrequent) Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/20 vision, corrected. (Continuous) Ability to match or discriminate between colors, normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film, etc. (Continuous) Ability to be qualified physically for respirator use, initially and annually. (Continuous)

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