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Medical University of South Carolina UNIV- Postdoctoral Scholar - Pathology & Lab in Charleston, South Carolina

FLSA: Salaried

Job Summary: Would like a motivated and skilled researcher for a Postdoctoral position. The chosen candidate will lead experiments on a federally funded 5-year project to investigate ‘lifestyle associated reactive metabolites and their negative impact on breast cancer risk’. Predominantly using cell line and dietary mouse models, the postdoctoral researcher will investigate the effects of Advanced Glycation End Products (AGEs) on epithelial-fibroblast cross talk in the mammary gland microenvironment and its consequences to breast cancer risk.

Payscale Salary Range: UNIV-Band 0: Commensurate with experience.

Job Duties:

  • 25% - To lead and/or develop research projects for the study of lifestyle factors on mammary gland development and neoplastic growth. - (Essential)

  • 25% - To lead, design and/or conduct experiments to characterize the impact of advanced glycation end products (AGEs) on the tumor microenvironment. - (Essential)

  • 25% - To execute and develop new experimental procedures using cutting edge 3D mimetas technology for investigating the important roles of fibroblasts and macrophages on cell communication with tumor cells. - (Essential)

  • 25% - To be responsible for teaching and supervising graduate students, research assistants and junior lab members to perform molecular and cellular biology assays including RNA isolation, real time pCR, cell isolation and culture from mouse mammary tissue and quantitative immunohistochemical assays - (Essential)

Preferred Experience & Additional Skills:

• PhD, MD, or MD/PhD required

• Requires an in-depth knowledge of relevant disciplines, processes or specialized fields

• Good oral and written communication skills

• Ability to work independently and as part of a team from culturally diverse backgrounds

• Prior experience in cancer biology, normal development or cell biology

• Track record of productivity and independence

• Experience with mouse models is preferred but not required

• Driven to be an independent scientist

Minimum Experience and Training Requirements:

Physical Requirements: Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb, using step stool. (Infrequent) Ability to work in temperature extremes (32? F to 100? F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs., unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted. (Frequent) Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted. (Infrequent) Ability to lift file boxes, from floor level to counter tops, unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted. (Infrequent) Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/20 vision, corrected. (Continuous) Ability to match or discriminate between colors, normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film, etc. (Continuous) Ability to be qualified physically for respirator use, initially and annually. (Continuous)